Inserm, the French National Institute of Health and Medical Research, is dedicated to enhancing the health and well-being of all individuals through the advancement of knowledge related to life and disease, innovation in treatment, and research in public health. At BioTis (U1026), an Inserm unit located in Bordeaux, a diverse team of scientists from Inserm, the National Center for Scientific Research (CNRS), research professors from the Université de Bordeaux, and clinicians from the University Hospital Center (CHU) are collaborating to conduct research spanning from the fundamental aspects of cell-cell and cell-matrix interactions, to bioprinting and biofabrication, and the development of translational models and clinical applications in vascular, orthopedic, oral, and maxillofacial surgery. This multidisciplinary approach has enabled significant advancements in these fields.
Role within Force Repair
Drawing on our expertise in establishing microfluidic coculture systems to investigate the interaction of sensory neurons with other cells or biomaterials, we will validate the capacity of the newly developed bioinks to support innervation by human induced pluripotent stem cell (iPSC)-derived sensory neurons in vitro and histological analyses to evaluate the extent of innervation following in vivo grafting.
